Vemurafenib (PLX4032), 200mg

Vemurafenib (PLX4032), 200mg

Vemurafenib (PLX4032), 10mM/1mL

Vemurafenib (PLX4032), 10mM/1mL

Vemurafenib (PLX4032), 1g

12.909,12 RON
SKU
SKM_S1267_1g

Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600Ewith IC50of 31 nM in cell-free assay. 10-fold selective for B-RafV600Eover wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.

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Description

Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600Ewith IC50of 31 nM in cell-free assay. 10-fold selective for B-RafV600Eover wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.