Limba
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Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600Ewith IC50of 31 nM in cell-free assay. 10-fold selective for B-RafV600Eover wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.
Price | 1.262,00 RON (preturile sunt fara TVA) |
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Description |
Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600Ewith IC50of 31 nM in cell-free assay. 10-fold selective for B-RafV600Eover wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy. |