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Selumetinib (AZD6244), 10mM/1mL
1.501,78 RON
SKU
SKM_S1008_10mM/1mL
Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEKinhibitor with IC50of 14 nM for MEK1 and Kdvalue of 530 nM for MEK2. It also inhibits ERK1/2 phosphorylation with IC50of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3.
| Price | 1.262,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEKinhibitor with IC50of 14 nM for MEK1 and Kdvalue of 530 nM for MEK2. It also inhibits ERK1/2 phosphorylation with IC50of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3. |
