Limba
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PT-179, an orthogonal Thalidomide derivative targets cereblonwithout causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein.
Price | 1.262,00 RON (preturile sunt fara TVA) |
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Description |
PT-179, an orthogonal Thalidomide derivative targets cereblonwithout causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein. |