PT-179, 5mg

PT-179, 5mg

PT-179, 100mg

PT-179, 100mg

PT-179, 25mg

3.431,96 RON
SKU
SKM_E1937_25mg

PT-179, an orthogonal Thalidomide derivative targets cereblonwithout causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein.

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Description

PT-179, an orthogonal Thalidomide derivative targets cereblonwithout causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein.