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Niraparib (MK-4827), 10mM/1mL
2.018,24 RON
SKU
SKM_S2741_10mM/1mL
Niraparib (MK-4827) is a selective inhibitor of PARP1/2with IC50of 3.8 nM/2.1 nM, with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It is >330-fold selective against PARP3, V-PARP and Tank1. Niraparib can form PARP–DNA complexes resulting in DNA damage, apoptosis, and cell death. Phase 3.
| Price | 1.696,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Niraparib (MK-4827) is a selective inhibitor of PARP1/2with IC50of 3.8 nM/2.1 nM, with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It is >330-fold selective against PARP3, V-PARP and Tank1. Niraparib can form PARP–DNA complexes resulting in DNA damage, apoptosis, and cell death. Phase 3. |
