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1,4-Dichlorobenzene, 25mg

1,4-Dichlorobenzene, 25mg

MPP+ iodide, 25mg

MPP+ iodide, 25mg

MPP+ iodide, 5mg

1.180,48 RON
SKU
SKM_S6301_5mg
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MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neuronsin substantia nigra. MPP+ induces autophagic cell deathin SH-SY5Y cells. MPP+ induces dopamine transporter (DAT)externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT)in serotonergic (5-HT) neurons.

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Description

MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neuronsin substantia nigra. MPP+ induces autophagic cell deathin SH-SY5Y cells. MPP+ induces dopamine transporter (DAT)externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT)in serotonergic (5-HT) neurons.
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