Limba
Romanian
Romanian
English|
Linifanib (ABT-869, AL39324, RG3635) is a novel, potent ATP-competitive VEGFR/PDGFRinhibitor for KDR, CSF-1R, Flt-1/3and PDGFRβ with IC50of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Linifanib (ABT-869) induces autophagyand apoptosis. Phase 3.
| Price | 844,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Linifanib (ABT-869, AL39324, RG3635) is a novel, potent ATP-competitive VEGFR/PDGFRinhibitor for KDR, CSF-1R, Flt-1/3and PDGFRβ with IC50of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Linifanib (ABT-869) induces autophagyand apoptosis. Phase 3. |
