Limba
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ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2and Bcl-wwith EC50of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. ABT-737 induces mitochondrial pathway apoptosisand mitophagy. Phase 2.
Price | 1.262,00 RON (preturile sunt fara TVA) |
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Description |
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2and Bcl-wwith EC50of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. ABT-737 induces mitochondrial pathway apoptosisand mitophagy. Phase 2. |