Limba
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(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6)and mitogen-activated protein kinasewith EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosisvia generation of reactive oxygen species (ROS)and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.
Price | 5.046,00 RON (preturile sunt fara TVA) |
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Description |
(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6)and mitogen-activated protein kinasewith EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosisvia generation of reactive oxygen species (ROS)and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells. |