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Romanian
Romanian
English|
Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3Kand mTORinhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagyand suppresses HIV-1replication. Phase 2.
| Price | 5.442,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3Kand mTORinhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagyand suppresses HIV-1replication. Phase 2. |
