Chitosan, 1g

Chitosan, 1g

CSRM617 hydrochloride, 25mg

CSRM617 hydrochloride, 25mg

CSRM617 hydrochloride, 5mg

1.180,48 RON
SKU
SKM_E4312_5mg

CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor)with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. It induces apoptosis by appearance of cleaved Caspase-3 and PARP and is well tolerated in the prostate cancer mouse model.

Mai multe informatii
Price 992,00 RON (preturile sunt fara TVA)
Description

CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor)with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. It induces apoptosis by appearance of cleaved Caspase-3 and PARP and is well tolerated in the prostate cancer mouse model.