CSRM617 hydrochloride, 5mg

CSRM617 hydrochloride, 5mg

L-Norvaline, 100mg

L-Norvaline, 100mg

CSRM617 hydrochloride, 25mg

2.614,43 RON
SKU
SKM_E4312_25mg

CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor)with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. It induces apoptosis by appearance of cleaved Caspase-3 and PARP and is well tolerated in the prostate cancer mouse model.

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Price 2.197,00 RON (preturile sunt fara TVA)
Description

CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor)with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. It induces apoptosis by appearance of cleaved Caspase-3 and PARP and is well tolerated in the prostate cancer mouse model.