Anti-SYP, mouse monoclonal, 0,1 ml, Species x-Reactivity: human, rat, Applications: IHC

Synaptophysin

Cat#: BSH-7385-100, 100ul,    BSH-7385-1, 1ml

Alias names: MRXSYP, SYP, Synaptophysin (p38), Optibodies, Optibody

MW:  33.8kDa

Substrate/Buffer: TRIS with 0.03% sodium azide, pH7,2

Clonality: Mouse monoclonal antibody

Clone: BS15

Application: IHC-P

S/R: Human, rabbit, rat, mouse, pig, sheep

Control tissues: Appendix, pancreas

Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

Synaptophysin - Appendix Appendix section has been stained using Synaptophysin optibody (Clone: BS15) with 1:300 dilution. Ganglion cells and neuronal axons stained strongly.		Synaptophysin - Appendix Appendix section has been stained using Synaptophysin optibody (Clone: BS15) with 1:300 dilution. Ganglion cells and neuronal axons stained strongly.		Synaptophysin – Neuro endrocrine tumor Neuro endocrine tumor section has been stained using Synaptophysin optibody (Clone: BS15) with 1:300 dilution. Neuroendocine tumor cells have intensive staining reaction.