Mouse Monoclonal Antibody to SOX10, 0,1 ml, Species x-Reactivity: human, Applications: IHC

SOX10

Cat#: BSH-7959-100, 100ul,   BSH-7959-1, 1ml

Clonality: Mouse monoclonal antibody

Clone: BS7

Application: IHC-P

S/R: Human

Control tissues: Breast (benign), skin, appendix

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. SOX10 is important and sensitive marker of melanoma especially for spindle cell and desmoplastic melanomas and schwannian neoplasms.

SOX10 - Breast (benign) Breast section has been stained using SOX10 optibody (Clone: BS7) with 1:200 dilution. Myoepithelial cells of breast have strong nuclear label.		SOX10 - Skin Skin section has been stained using SOX10 opibody (Clone: BS7) with 1:200 dilution. Melanocytes have strong staining reaction.		SOX10 – Melanoma Melanoma section has been stained using SOX10 optibody (Clone: BS7) with 1:200 dilution. Melanoma cells have strong nuclear label.