Limba
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Buparlisib (BKM120, NVP-BKM120) is a selective PI3Kinhibitor of p110α/β/δ/γwith IC50of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.
Price | 5.442,00 RON (preturile sunt fara TVA) |
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Description |
Buparlisib (BKM120, NVP-BKM120) is a selective PI3Kinhibitor of p110α/β/δ/γwith IC50of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2. |