Limba
Romanian
Romanian
English|
Brevilin A (6-O-Angeloylplenolina), a sesquiterpene lactone isolated from Centipeda minima, is a selective inhibitor of STAT3and attenuates the JAKsactivity by blocking the JAKs tyrosine kinase domain JH1. Brevilin A induces apoptosisand autophagyof colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation.
| Price | 2.307,00 RON (preturile sunt fara TVA) |
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| Description |
Brevilin A (6-O-Angeloylplenolina), a sesquiterpene lactone isolated from Centipeda minima, is a selective inhibitor of STAT3and attenuates the JAKsactivity by blocking the JAKs tyrosine kinase domain JH1. Brevilin A induces apoptosisand autophagyof colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation. |
