Oleandrin (PBI-05204), 5mg

Oleandrin (PBI-05204), 5mg

Brevilin A, 5mg

Brevilin A, 5mg

Brevilin A, 1mg

1.180,48 RON
SKU
SKM_S6919_1mg

Brevilin A (6-O-Angeloylplenolina), a sesquiterpene lactone isolated from Centipeda minima, is a selective inhibitor of STAT3and attenuates the JAKsactivity by blocking the JAKs tyrosine kinase domain JH1. Brevilin A induces apoptosisand autophagyof colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation.

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Description

Brevilin A (6-O-Angeloylplenolina), a sesquiterpene lactone isolated from Centipeda minima, is a selective inhibitor of STAT3and attenuates the JAKsactivity by blocking the JAKs tyrosine kinase domain JH1. Brevilin A induces apoptosisand autophagyof colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation.