GSK2606414, 10mM/1mL

GSK2606414, 10mM/1mL

BAY 87-2243, 50mg

BAY 87-2243, 50mg

BAY 87-2243, 10mg

1.370,88 RON
SKU
SKM_S7309_10mg

BAY 87-2243 is a potent and selective hypoxia-inducible factor-1 (HIF-1)inhibitor. BAY 87-2243 inhibits mitochondrial complex Iactivity, thus triggering a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis. BAY 87-2243 exerts antitumor activity. Phase 1.

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Description

BAY 87-2243 is a potent and selective hypoxia-inducible factor-1 (HIF-1)inhibitor. BAY 87-2243 inhibits mitochondrial complex Iactivity, thus triggering a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis. BAY 87-2243 exerts antitumor activity. Phase 1.