YUM70, 5mg

YUM70, 5mg

YUM70, 10mM/1mL

YUM70, 10mM/1mL

YUM70, 25mg

4.028,15 RON
SKU
SKM_S6193_25mg

YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78)inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.Although YUM70 inhibits GRP78 enzymatic activity, it increases the expression of GRP78 by increasing the chaperone translation mechanism.

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Description

YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78)inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.Although YUM70 inhibits GRP78 enzymatic activity, it increases the expression of GRP78 by increasing the chaperone translation mechanism.