XL147 analogue, 10mg

XL147 analogue, 10mg

Cabozantinib (XL184), 5mg

Cabozantinib (XL184), 5mg

XL147 analogue, 50mg

3.255,84 RON
SKU
SKM_S1118_50mg

XL147 analogue (SAR245408) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γwith IC50of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. XL147 analogue induces apoptosis. Phase 1/2.

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Description

XL147 analogue (SAR245408) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γwith IC50of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. XL147 analogue induces apoptosis. Phase 1/2.