Limba
Romanian
Romanian
English|
WYE-687 is an ATP-competitive and selective inhibitor of mTORwith IC50of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
| Price | 1.658,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
WYE-687 is an ATP-competitive and selective inhibitor of mTORwith IC50of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold). |
