Evofosfamide (TH-302), 10mM/1mL

Evofosfamide (TH-302), 10mM/1mL

Wortmannin, 20mg

Wortmannin, 20mg

Wortmannin, 5mg

1.180,48 RON
SKU
SKM_S2758_5mg

Wortmannin is the first described PI3Kinhibitor with IC50of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosomeformation and potently inhibits DNA-PK/ATMwith IC50of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1activity.

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Description

Wortmannin is the first described PI3Kinhibitor with IC50of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosomeformation and potently inhibits DNA-PK/ATMwith IC50of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1activity.