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VU0071063, 5mg

1.514,87 RON
SKU
SKM_S6978_5mg

VU0071063 activates heterologously expressed Kir6.2/SUR1 channelswith a EC50 of 7 μM, dose dependently and reversibly hyperpolarizes the β-cell membrane potential, which, in turn, inhibits glucose-stimulated Ca2+ entry and insulin secretion. 

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Description

VU0071063 activates heterologously expressed Kir6.2/SUR1 channelswith a EC50 of 7 μM, dose dependently and reversibly hyperpolarizes the β-cell membrane potential, which, in turn, inhibits glucose-stimulated Ca2+ entry and insulin secretion.