GW441756, 10mM/1mL

GW441756, 10mM/1mL

NU7026, 10mg

NU7026, 10mg

VU 0361737, 10mg

813,96 RON
SKU
SKM_S2892_10mg

VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4receptor with EC50of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.

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Description

VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4receptor with EC50of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.