Limba
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VER155008 is a potent Hsp70family inhibitor with IC50of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78 (HSPA5, Bip), respectively, >100-fold selectivity over HSP90. VER155008 inhibits autophagyand causes reduced levels of HSP90 client proteins.
Price | 21.656,00 RON (preturile sunt fara TVA) |
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Description |
VER155008 is a potent Hsp70family inhibitor with IC50of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78 (HSPA5, Bip), respectively, >100-fold selectivity over HSP90. VER155008 inhibits autophagyand causes reduced levels of HSP90 client proteins. |