Limba
|
Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Kiof <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Venetoclax is reported to induce cell growth suppression, apoptosis, cell cycle arrest, and autophagyin triple negative breast cancer MDA-MB-231 cells. Phase 3.
Price | 1.658,00 RON (preturile sunt fara TVA) |
---|---|
Description |
Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Kiof <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Venetoclax is reported to induce cell growth suppression, apoptosis, cell cycle arrest, and autophagyin triple negative breast cancer MDA-MB-231 cells. Phase 3. |