Nesolicaftor (PTI-428), 1mg

Nesolicaftor (PTI-428), 1mg

Vacuolin-1, 25mg

Vacuolin-1, 25mg

Vacuolin-1, 5mg

1.180,48 RON
SKU
SKM_S6912_5mg

Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca(2+)-dependent exocytosis of lysosomesand prevents the release of lysosomal content without affecting the process of resealing. Vacuolin-1 is also a potent and selective PIKfyveinhibitor, and inhibits autophagyby impairing lysosomal maturation via PIKfyve inhibition.

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Description

Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca(2+)-dependent exocytosis of lysosomesand prevents the release of lysosomal content without affecting the process of resealing. Vacuolin-1 is also a potent and selective PIKfyveinhibitor, and inhibits autophagyby impairing lysosomal maturation via PIKfyve inhibition.