URMC-099, 25mg

URMC-099, 25mg

JSH-23, 5mg

JSH-23, 5mg

URMC-099, 10mM/1mL

1.501,78 RON
SKU
SKM_S7343_10mM/1mL

URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK)inhibitor with IC50of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2activity with IC50of 11 nM. URMC-099 also inhibits ABL1with IC50 of 6.8 nM. URMC-099 induces autophagy.

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Price 1.262,00 RON (preturile sunt fara TVA)
Description

URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK)inhibitor with IC50of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2activity with IC50of 11 nM. URMC-099 also inhibits ABL1with IC50 of 6.8 nM. URMC-099 induces autophagy.