Unesbulin (PTC596), 1g

Unesbulin (PTC596), 1g

GSK3179106, 2mg

GSK3179106, 2mg

Unesbulin (PTC596), 10mM/1mL

3.111,85 RON
SKU
SKM_S8820_10mM/1mL

Unesbulin (PTC596) is a second-generation BMI-1inhibitor that accelerates BMI-1 degradation. PTC596 downregulates MCL-1and induces p53-independent mitochondrial apoptosis. IC50 values at 72 hours ranged from 68 to 340 nM in mantle cell lymphoma (MCL) cell lines.

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Description

Unesbulin (PTC596) is a second-generation BMI-1inhibitor that accelerates BMI-1 degradation. PTC596 downregulates MCL-1and induces p53-independent mitochondrial apoptosis. IC50 values at 72 hours ranged from 68 to 340 nM in mantle cell lymphoma (MCL) cell lines.