Atuzabrutinib, 1g

Atuzabrutinib, 1g

UNC8153, 25mg

UNC8153, 25mg

UNC8153, 5mg

1.501,78 RON
SKU
SKM_E1613_5mg

UNC8153 is a selective degrader of nuclear receptor-binding SET domain-containing 2 (NSD2)with a binding Kd of 24 nM, effectively reducing NSD2 protein levels and the dimethylate lysine 36 of histone 3 (H3K36me2) chromatin mark. Its simple warhead promotes proteasome-dependent degradation of NSD2 via a novel mechanism.

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Price 1.262,00 RON (preturile sunt fara TVA)
Description

UNC8153 is a selective degrader of nuclear receptor-binding SET domain-containing 2 (NSD2)with a binding Kd of 24 nM, effectively reducing NSD2 protein levels and the dimethylate lysine 36 of histone 3 (H3K36me2) chromatin mark. Its simple warhead promotes proteasome-dependent degradation of NSD2 via a novel mechanism.