Limba
Romanian
Romanian
English|
UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2and EZH1with IC50of 2 nM and 45 nM in cell-free assays, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets. UNC1999 is a potent autophagyinducer. UNC1999 specifically suppresses H3K27me3/2 and induces a range of anti-leukemia effects including anti-proliferation, differentiation, and apoptosis.
| Price | 1.262,00 RON (preturile sunt fara TVA) |
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| Description |
UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2and EZH1with IC50of 2 nM and 45 nM in cell-free assays, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets. UNC1999 is a potent autophagyinducer. UNC1999 specifically suppresses H3K27me3/2 and induces a range of anti-leukemia effects including anti-proliferation, differentiation, and apoptosis. |
