UGT8-IN-1, 1mg

UGT8-IN-1, 1mg

UGT8-IN-1, 25mg

UGT8-IN-1, 25mg

UGT8-IN-1, 5mg

2.470,44 RON
SKU
SKM_E4592_5mg

UGT8-IN-1 is a brain-penetrable and orally active inhibitor of ceramide galactosyltransferase enzyme (UGT8). UGT8-IN-1 targets sulfatide metabolism resulting in ceramide-induced lethal mitophagy and subsequent cancer cell death in vitro, and reduces tumour growth in mutant Kras; Gnas allografts.

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Description

UGT8-IN-1 is a brain-penetrable and orally active inhibitor of ceramide galactosyltransferase enzyme (UGT8). UGT8-IN-1 targets sulfatide metabolism resulting in ceramide-induced lethal mitophagy and subsequent cancer cell death in vitro, and reduces tumour growth in mutant Kras; Gnas allografts.