L-Fucitol, 1mg

L-Fucitol, 1mg

UCB-9260, 25mg

UCB-9260, 25mg

UCB-9260, 5mg

2.221,73 RON
SKU
SKM_S3231_5mg

UCB-9260 is an orally active inhibitor that inhibits TNFsignalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13  nM. UCB-9260 also inhibits NF-κBwith IC50 of 202 nM after TNF stimulation.

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Description

UCB-9260 is an orally active inhibitor that inhibits TNFsignalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13  nM. UCB-9260 also inhibits NF-κBwith IC50 of 202 nM after TNF stimulation.