Limba
Romanian
Romanian
English|
TP0427736 HCl, 10mM/1mL
2.143,19 RON
SKU
SKM_S8700_10mM/1mL
TP0427736 is a potent inhibitor of ALK5 kinase activitywith an IC50of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM.
| Price | 1.801,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
TP0427736 is a potent inhibitor of ALK5 kinase activitywith an IC50of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM. |
