TMZ(Temozolomide), 10g

TMZ(Temozolomide), 10g

Tamoxifen, 1g

Tamoxifen, 1g

TMZ(Temozolomide), 10mM/1mL

1.501,78 RON
SKU
SKM_S1237_10mM/1mL

TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosisand exhibits antitumor activity.

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Description

TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosisand exhibits antitumor activity.