TH287, 50mg

TH287, 50mg

Lomitapide Mesylate, 10mg

Lomitapide Mesylate, 10mg

TH588, 5mg

1.180,48 RON
SKU
SKM_S7632_5mg

TH588 is a potent and selective MTH1 (NUDT1)inhibitor with IC50of 5 nM. It has no relevant inhibition of any of the other tested proteins at 100 μM, although TH588 showed reasonable selectivity when tested on a much larger panel of 87 enzymes, GPCRs, kinases, ion channels and transporters at 10 μM.

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Description

TH588 is a potent and selective MTH1 (NUDT1)inhibitor with IC50of 5 nM. It has no relevant inhibition of any of the other tested proteins at 100 μM, although TH588 showed reasonable selectivity when tested on a much larger panel of 87 enzymes, GPCRs, kinases, ion channels and transporters at 10 μM.