Limba
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Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2)agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).
Price | 723,00 RON (preturile sunt fara TVA) |
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Description |
Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2)agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively). |