Tanespimycin (17-AAG), 10mM/1mL

Tanespimycin (17-AAG), 10mM/1mL

Alvespimycin (17-DMAG) HCl, 25mg

Alvespimycin (17-DMAG) HCl, 25mg

Tanespimycin (17-AAG), 5mg

1.180,48 RON
SKU
SKM_S1141_5mg

Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90inhibitor with IC50of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagyand mitophagy. Phase 3.

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Description

Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90inhibitor with IC50of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagyand mitophagy. Phase 3.