Sunitinib malate, 500mg

Sunitinib malate, 500mg

Sunitinib malate, 10mM/1mL

Sunitinib malate, 10mM/1mL

Sunitinib malate, 1g

4.721,92 RON
SKU
SKM_S1042_1g

Sunitinib malate is a multi-targeted RTKinhibitor targeting VEGFR2 (Flk-1)and PDGFRβwith IC50of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptorand mitochondrial-dependent apoptosis.

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Description

Sunitinib malate is a multi-targeted RTKinhibitor targeting VEGFR2 (Flk-1)and PDGFRβwith IC50of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptorand mitochondrial-dependent apoptosis.