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SPP-86, 5mg

2.156,28 RON
SKU
SKM_E2401_5mg

SPP-86, a potent and selective cell permeable inhibitor of rearranged during transfection (RET) tyrosine kinasewith an IC50 of 8 nM, inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Aktand MAPKsignaling, also inhibits RET-induced estrogen receptorα (ERα)phosphorylation in MCF7 cells.

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Description

SPP-86, a potent and selective cell permeable inhibitor of rearranged during transfection (RET) tyrosine kinasewith an IC50 of 8 nM, inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Aktand MAPKsignaling, also inhibits RET-induced estrogen receptorα (ERα)phosphorylation in MCF7 cells.