Sorafenib tosylate, 200mg

Sorafenib tosylate, 200mg

STF-62247, 10mg

STF-62247, 10mg

Sorafenib tosylate, 10mM/1mL

2.496,62 RON
SKU
SKM_S1040_10mM/1mL

Sorafenib tosylate is a multikinase inhibitor of Raf-1and B-Rafwith IC50of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3and c-KITwith IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagyand apoptosisand activates ferroptosiswith anti-tumor activity.

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Description

Sorafenib tosylate is a multikinase inhibitor of Raf-1and B-Rafwith IC50of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3and c-KITwith IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagyand apoptosisand activates ferroptosiswith anti-tumor activity.