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Romanian
Romanian
English|
Sorafenib is a multikinase inhibitor of Raf-1and B-Rafwith IC50of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3and c-KITwith IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagyand apoptosisand activates ferroptosiswith anti-tumor activity.
| Price | 2.884,00 RON (preturile sunt fara TVA) |
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| Description |
Sorafenib is a multikinase inhibitor of Raf-1and B-Rafwith IC50of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3and c-KITwith IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagyand apoptosisand activates ferroptosiswith anti-tumor activity. |
