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Sodium stibogluconate, 200mg

1.180,48 RON
SKU
SKM_S2435_200mg

Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001), a pentavalent antimony derivative, is a potent and selective inhibitor of protein tyrosine phosphatase (PTPase). Sodium stibogluconate inhibits 99% of Src homology 2 domain-containing phosphatase 1 (SHP-1)activity at 10 μg/ml and similar degrees of inhibition of SHP-2and PTP1Brequires 100 μg/ml. Sodium stibogluconate is a drug used in treatment of leishmaniasis.

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Description

Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001), a pentavalent antimony derivative, is a potent and selective inhibitor of protein tyrosine phosphatase (PTPase). Sodium stibogluconate inhibits 99% of Src homology 2 domain-containing phosphatase 1 (SHP-1)activity at 10 μg/ml and similar degrees of inhibition of SHP-2and PTP1Brequires 100 μg/ml. Sodium stibogluconate is a drug used in treatment of leishmaniasis.