Silmitasertib (CX-4945), 50mg

Silmitasertib (CX-4945), 50mg

Silmitasertib (CX-4945), 10mM/1mL

Silmitasertib (CX-4945), 10mM/1mL

Silmitasertib (CX-4945), 1g

25.770,64 RON
SKU
SKM_S2248_1g

Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2)with IC50of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Silmitasertib induces autophagyand promotes apoptosis. Phase 1/2.

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Description

Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2)with IC50of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Silmitasertib induces autophagyand promotes apoptosis. Phase 1/2.