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SEC inhibitor KL-1, 25mg
4.858,77 RON
SKU
SKM_S2973_25mg
SEC inhibitor KL-1 (KL-1) is a potent and selective inhibitor of super elongation complex (SEC)that disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. KL-1 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with Ki of 3.48 μM.
| Price | 4.083,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
SEC inhibitor KL-1 (KL-1) is a potent and selective inhibitor of super elongation complex (SEC)that disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. KL-1 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with Ki of 3.48 μM. |
