Adezmapimod (SB203580), 10mM/1mL

Adezmapimod (SB203580), 10mM/1mL

SB202190, 1g

SB202190, 1g

SB202190, 25mg

1.200,32 RON
SKU
SKM_S1077_25mg

SB202190 is a potent p38 MAPK inhibitor targeting p38α/βwith IC50of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosisvia induction of autophagyand heme oxygenase-1. SB202190 significantly suppresses Erastin‐dependent ferroptosis.

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Description

SB202190 is a potent p38 MAPK inhibitor targeting p38α/βwith IC50of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosisvia induction of autophagyand heme oxygenase-1. SB202190 significantly suppresses Erastin‐dependent ferroptosis.