Limba
Romanian
Romanian
English|
SB202190 is a potent p38 MAPK inhibitor targeting p38α/βwith IC50of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosisvia induction of autophagyand heme oxygenase-1. SB202190 significantly suppresses Erastin‐dependent ferroptosis.
| Price | 1.262,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
SB202190 is a potent p38 MAPK inhibitor targeting p38α/βwith IC50of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosisvia induction of autophagyand heme oxygenase-1. SB202190 significantly suppresses Erastin‐dependent ferroptosis. |
