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Ruxolitinib Phosphate, 25mg
1.180,48 RON
SKU
SKM_S5243_25mg
Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2inhibitor to enter the clinic with IC50of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagyand enhances apoptosis.
| Price | 992,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2inhibitor to enter the clinic with IC50of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagyand enhances apoptosis. |
