Rimiducid (AP1903), 100mg

Rimiducid (AP1903), 100mg

Ac-YVAD-cmk, 5mg

Ac-YVAD-cmk, 5mg

Rimiducid (AP1903), 10mM/1mL

3.255,84 RON
SKU
SKM_S9726_10mM/1mL

Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion proteinwhile binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.

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Description

Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion proteinwhile binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.